Uses, Side Effects, Interactions, Pictures, Warnings & Dosing

We save you Time & Money from having to visit your doctor, Your Free Medical Review and Prescription is included in Our Price. Sildenafil protects cyclic guanosine monophosphate (cGMP) from degradation by cGMP-specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum Nitric oxide (NO) in the corpus cavernosum of the penis binds to guanylate cyclase receptors, which results in increased levels of cGMP, leading to smooth muscle relaxation ( vasodilation ) of the intimal cushions of the helicine arteries This smooth muscle relaxation leads to vasodilation and increased inflow of blood into the spongy tissue of the penis, causing an erection. 35 Robert F. Furchgott , Ferid Murad , and Louis Ignarro won the Nobel Prize in Physiology or Medicine in 1998 for their independent study of the metabolic pathway of nitric oxide in smooth muscle vasodilation.

There's one very simple rule that you should remember ahead of the rest - don't take more than one 100mg pill in 24 hours. Besides, you should avoid taking Viagra along with other ED meds or with nitrate drugs used to treat chest pain (angina). Moreover, you should avoid eating grapefruit or drinking grapefruit juice when on Viagra because it might make the concentration of Sildenafil in your system rise beyond safe levels.

In case of VigRX the scientific knowledgebase is not that extensive - the requirements to a herbal preparation are way less sophisticated; this way or the other, VigRX effect is accumulated gradually within weeks and cialis lugano months (according to the official website, the effect is built within 30 - 90 days). Plus, you should keep in mind the fact that natural supplements are more likely to provide the desired results along with the changes in lifestyle (giving up bad habits, adding physical exercising, adjusting your diet and etc.).

The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Based on efficacy and tolerability, the dose may be increased to 100 mg or decreased to 25 mg. The maximum recommended dose is 100 mg. The maximum recommended dosing frequency is once per day. If VIAGRA is taken with food, the onset of activity may be delayed compared to the fasted state (see section 5.2).

What is more interesting to me is the role of NO on muscles during resistance training. JE Anderson found that NO appears to be a vital signal in the activation of muscle satellite cells in response to damage. Satellite cell activation is the key first step in the repair and hypertrophy of muscle cells after heavy training. Viagra may therefore enhance the hypertrophy response to exercise, working at the most basic and primary level of the process.